Clinical spectrum and management implications of left ventricular outflow obstruction with mild ventricular septal thickness in hypertrophic cardiomyopathy. The following are key perspectives from the 2020 American Heart Association/American College of Cardiology (AHA/ACC) guideline for the management of patients with hypertrophic cardiomyopathy (HCM): Clinical Topics: Anticoagulation Management, Arrhythmias and Clinical EP, Congenital Heart Disease and Pediatric Cardiology, Heart Failure and Cardiomyopathies, Invasive Cardiovascular Angiography and Intervention, Noninvasive Imaging, Prevention, Sports and Exercise Cardiology, Atherosclerotic Disease (CAD/PAD), Anticoagulation Management and Atrial Fibrillation, Implantable Devices, SCD/Ventricular Arrhythmias, Atrial Fibrillation/Supraventricular Arrhythmias, Congenital Heart Disease, CHD and Pediatrics and Arrhythmias, CHD and Pediatrics and Imaging, CHD and Pediatrics and Interventions, CHD and Pediatrics and Quality Improvement, Acute Heart Failure, Interventions and Coronary Artery Disease, Interventions and Imaging, Interventions and Structural Heart Disease, Angiography, Echocardiography/Ultrasound, Magnetic Resonance Imaging, Nuclear Imaging, Sports and Exercise and Congenital Heart Disease and Pediatric Cardiology, Sports and Exercise and Imaging, Keywords: Adrenergic beta-Antagonists, Anticoagulants, Arrhythmias, Cardiac, Atrial Fibrillation, Cardiomyopathy, Hypertrophic, Coronary Artery Disease, Coronary Angiography, Death, Sudden, Cardiac, Defibrillators, Implantable, Diagnostic Imaging, Echocardiography, Electrocardiography, Genetic Testing, Heart Failure, Magnetic Resonance Imaging, Myocardial Ischemia, Physical Examination, Pregnancy, Risk Factors, Secondary Prevention, Sports, Heart Defects, Congenital. Prognostic implications of defibrillation threshold testing in patients with hypertrophic cardiomyopathy. Subcutaneous implantable cardioverter defibrillator in patients with hypertrophic cardiomyopathy: an initial experience. Comparison of Valsalva manoeuvre and exercise in echocardiographic evalu.ation of left ventricular outflow tract obstruction in hypertrophic cardiomyopathy. Whole genome sequencing improves outcomes of genetic testing in patients with hypertrophic cardiomyopathy. Long-term outcomes of combined epicardial and endocardial ablation of monomorphic ventricular tachycardia related to hypertrophic cardiomyopathy. Hospital volume outcomes after septal myectomy and alcohol septal ablation for treatment of obstructive hypertrophic cardiomyopathy: US nationwide inpatient database, 2003-2011. Relation between severity of left-ventricular hypertrophy and prognosis in patients with hypertrophic cardiomyopathy. The expert peer review of AHA-commissioned documents (eg, scientific statements, clinical practice guidelines, systematic reviews) is conducted by the AHA Office of Science Operations. Risk factors for lethal arrhythmic events in children and adolescents with hypertrophic cardiomyopathy and an implantable defibrillator: an international multicenter study. This slide set is adapted from the 2020 AHA/ACC Guideline for the Diagnosis and Treatment of Patients with Hypertrophic Cardiomyopathy. If surgical septal reduction is contraindicated, alcohol septal ablation can be considered at experienced centers. Interventions and Coronary Artery Disease. Whether an individual patient with HCM wishes to pursue more rigorous exercise/training is dependent on a comprehensive shared discussion between that patient and their expert HCM care team regarding the potential risks of that level of training/participation but with the understanding that exercise-related risk cannot be individualized for a given patient. Effects of diltiazem on myocardial perfusion abnormalities during exercise in patients with hypertrophic cardiomyopathy Ann Nucl Med. Percutaneous transluminal septal myocardial ablation in hypertrophic obstructive cardiomyopathy: results with respect to intraprocedural myocardial contrast echocardiography. Long-term survival in patients with resting obstructive hypertrophic cardiomyopathy comparison of conservative versus invasive treatment. For pregnant HCM patients, BBs should be continued with monitoring of fetal growth and care should be coordinated between cardiology and obstetrics. II. Congenital Heart Disease and Pediatric Cardiology, Invasive Cardiovascular Angiography and Intervention, Pulmonary Hypertension and Venous Thromboembolism, CardioSource Plus for Institutions and Practices, Nuclear Cardiology and Cardiac CT Meeting on Demand, Annual Scientific Session and Related Events, ACC Quality Improvement for Institutions Program, National Cardiovascular Data Registry (NCDR). ACC/AHA Applying Class of Recommendation and Level of Evidence to Clinical Strategies, Interventions, Treatments, or Diagnostic Testing in Patient Care (Updated May 2019)*, Tables in this section are located in the full guideline.1. Specific treatments are not available for most patients with IDC. Hypertrophic remodelling in cardiac regulatory myosin light chain (MYL2) founder mutation carriers. Verapamil prevents silent myocardial perfusion abnormalities during exercise in asymptomatic patients with hypertrophic cardiomyopathy. This article has been copublished in the Journal of the American College of Cardiology. Competitive sport participation among athletes with heart disease: a call for a paradigm shift in decision making. 10. Genetic counselling and testing in cardiomyopathies: a position statement of the European Society of Cardiology Working Group on Myocardial and Pericardial Diseases. Screening and Risk Identification. Quit smoking. Phenotypic spectrum and patterns of left ventricular hypertrophy in hypertrophic cardiomyopathy: morphologic observations and significance as assessed by two-dimensional echocardiography in 600 patients. Left ventricular assist device therapy in patients with restrictive and hypertrophic cardiomyopathy. As rapid atrial fibrillation is often poorly tolerated in patients with HCM, maintenance of sinus rhythm and rate control are key pursuits in successful treatment. 2. 2020 AHA/ACC Guideline for the Diagnosis and Treatment of Patients With Hypertrophic Cardiomyopathy: Executive Summary: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines Management of Patients With HCM and Ventricular Arrhythmias e546, 5.5. Survival after alcohol septal ablation in patients with hypertrophic obstructive cardiomyopathy. Shared decision-making, a dialogue between patients and their care team that includes full disclosure of all testing and treatment … Management of Patients With HCM and Advanced HF e546, 6. Exercise. Survival after cardiac arrest or sustained ventricular tachycardia in patients with hypertrophic cardiomyopathy. Echo-guided percutaneous septal ablation for symptomatic hypertrophic obstructive cardiomyopathy: 7 years of experience. Relation of electrocardiographic abnormalities to evolving left ventricular hypertrophy in hypertrophic cardiomyopathy during childhood. Asymmetric septal hypertrophy in patients with severe aortic stenosis: the usefulness of associated septal myectomy. International external validation study of the 2014 European Society of Cardiology guidelines on sudden cardiac death prevention in hypertrophic cardiomyopathy (EVIDENCE-HCM). Get modest exercise after discussing with your doctor the most appropriate program of physical activity. Hypertrophic cardiomyopathy phenotype revisited after 50 years with cardiovascular magnetic resonance. Your doctor will discuss with you the most appropriate treatment for your condition.The options include: 1. Hypertrophic cardiomyopathy in pediatric patients: effect of verapamil on regional and global left ventricular diastolic function. For symptomatic patients without provoked gradients, an exercise echocardiogram should be performed. Pulmonary hypertension is associated with worse survival in hypertrophic cardiomyopathy. Diagnosis, Initial Evaluation, and Follow-up e537, 3.3. Clinical significance of late gadolinium enhancement in patients <20 years of age with hypertrophic cardiomyopathy. Cardiac resynchronization therapy in patients with end-stage hypertrophic cardiomyopathy. [email protected]com. American College of Cardiology and American Heart Association. Antihypertensive therapy in hypertrophic cardiomyopathy. Direct oral anticoagulants in patients with hypertrophic cardiomyopathy and atrial fibrillation. Impact of septal reduction on left atrial size and diastole in hypertrophic cardiomyopathy. Cardiac resynchronization therapy for end-stage hypertrophic cardiomyopathy: the need for disease-specific criteria. Determining pathogenicity of genetic variants in hypertrophic cardiomyopathy: importance of periodic reassessment. Evaluation of left ventricular filling pressures by doppler echocardiography in patients with hypertrophic cardiomyopathy. ICD patient selection. Stress cardiomyopathy can be classified according to either primary or secondary form, depending on whether it is the primary reason of care-seeking (primary form) or the patient is already in the health care setting during evaluation or treatment … Patients’ participation in medical care: effects on blood sugar control and quality of life in diabetes. Implantable cardioverter-defibrillators and prevention of sudden cardiac death in hypertrophic cardiomyopathy. Prediction of sudden death risk in obstructive hypertrophic cardiomyopathy: potential for refinement of current criteria. Tables in this section are located in the full guideline.1Figure 4 presents a management diagram of symptoms in patients with HCM. The full guideline1 recommends a combination of lifestyle modifications, medications, and surgical/catheter interventions that constitute components of guideline-directed medical therapy. Top 10 Take-Home Messages– 2020 AHA/ACC Guideline for the Diagnosis and Treatment of Patients With Hypertrophic Cardiomyopathy. Clinical genetic testing in pediatric cardiomyopathy: is bigger better?. Because of the preponderance of genetic influences on cardiomyopathy, it is generally recommended that patients with any cardiomyopathy be referred for genetic counseling, especially if … HCM indicates hypertrophic cardiomyopathy; LB/B, likely benign/benign; LP/P, likely pathogenic or pathogenic; and VUS, variant of unknown significance. Treatment for your condition.The options include: 1 sports is recommended followed by ECG. Factors for lethal arrhythmic events in children with hypertrophic cardiomyopathy during childhood monitoring: crucial implications genetic... 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